Prevalence and Antifungal Susceptibility of Fungal Isolates  Associated with Otomycotic Patients in Lafia

Auteur/ices

  • Aleruchi Chuku
    Department of Microbiology, Federal University of Lafia
  • Bashiru Eya Sani
    Department of Microbiology, Federal University of Lafia
    https://orcid.org/0000-0002-2983-3861
  • Pedro Akharenegbe
    Department of Science Laboratory Technology, Federal University of Lafia
  • Godwin Attah Obande
    Department of Microbiology, Federal University of Lafia

Mots-clés :

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Résumé

This study assessed the fungal pathogens associated with otomycosis and their antifungal profile. A cross-sectional study was done to collect, examine and culture 177 exudate swabs from patients presenting with otomycosis at the Dalhatu Araf Specialist Hospital for three months. Fungal isolates were identified using their morphological and microscopic structure and characteristics. Mycological assessments showed that 20.90% were positive for fungal agents. Males (70.27%) had more positive cases than females (29.73%). Age group 31-40 had the most predominant number of cases (49.95%) than any other age group. A. niger  (51.35%) was the most predominant, followed by Candida spp. (32.43%), while A. flavus (16.22%) was the least prevalent. The month of May had the most positive cases (16; 43.24%), and March had the least (24.32%). Antifungal assay showed varied susceptibility of the isolates to the antifungals. A. flavus showed no resistance to Itraconazole. However, multiple drug resistance was observed amongst the samples, with A. niger showing high resistance to ketoconazole and fluconazole. This study showed that A. niger, A. flavus and Candida spp. are etiological agents associated with otomycosis in Lafia. Caution also needs to be taken in managing this infection as multiple drug resistance was also observed.

Dimensions

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Publiée

2023-10-31

Comment citer

Prevalence and Antifungal Susceptibility of Fungal Isolates  Associated with Otomycotic Patients in Lafia. (2023). Lafia Journal of Scientific and Industrial Research, 1(1 & 2), 25-28. https://doi.org/10.62050/ljsir2023.v1n1.237

Numéro

Volume 1, Issue 1 & 2 (October, 2023), Lafia Journal of Scientific and Industrial Research (LJSIR)

Rubrique

Life Sciences
Copyright & Licensing

Merci de créditer les auteurs lors de toute citation : Lafia Journal of Scientific and Industrial Research (2023)

Creative Commons License

Ce travail est disponible sous licence Creative Commons Attribution - Pas d’Utilisation Commerciale - Partage dans les Mêmes Conditions 4.0 International.

Comment citer

Prevalence and Antifungal Susceptibility of Fungal Isolates  Associated with Otomycotic Patients in Lafia. (2023). Lafia Journal of Scientific and Industrial Research, 1(1 & 2), 25-28. https://doi.org/10.62050/ljsir2023.v1n1.237

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